Haematology  |  Management of CLL Pathway - Referral Criteria


Management of CLL Pathway - Referral Criteria

Refer to haematology if:

  1. Stage A without symptoms + any one of:
    1. Progressive lymphadenopathy or hepatosplenomegaly (nodes >2cm enlargement)
    2. Progressive fall in Hb or platelets. If Hb falls, consider autoimmune haemolytic anaemia (AIHA). Check for evidence of red cell destruction (reticulocytes, LDH, bilirubin, coombs test)
    3. Lymphocyte count doubles in less than 6 months (and the baseline count is >20 x 109/L). The absolute lymphocyte count can rise >200 x109/l and is not by itself a reason to start treatment if this is a slow rise and not associated with cytopenias.
    4. Hypogammaglobulinaemia associated with recurrent infections
    5. Weight loss >10%, extreme fatigue or sweats (exclude other causes)
  2. Stage A with symptoms
  3. Stage B or C
  4. Any stage & under 50 years old

Last updated : Wednesday, September 05, 2018
Next review date : Thursday, September 05,2019

Disclaimer: This site is intended to be flexible and frequently updated. While every effort has been made to ensure accuracy, all information should be verified.