Colorectal Cancer Pathway - Risk Factors
1. Age >50:
- The risk of CRC increases with age. Over 90% of cases are in individuals over the age of 50 years.
2. Past history adenoma/ CRC/IBD:
- An increased risk of CRC is identified in individuals with a personal history of CRC, colorectal adenomas or inflammatory bowel disease.
- Studies suggest that individuals with longstanding (>10yrs), extensive Ulcerative Colitis or Crohns Disease have a CRC risk of 2% by 10yrs, 8% by 20yrs and 18% by 30years.
3. Family History CRC:
- Individuals with a family history of CRC may have an increased risk of developing disease. A full family history is needed and should include any CRC or adenomas in 1st or 2nd degree relatives and the age of diagnosis.
- 1st degree relatives- parents, siblings, children.
- 2nd degree relative- grandparents, aunts, uncles, nieces, nephews. For more information on risk see the CRC Surveillance recommendations
Last updated : Wednesday, November 25, 2015
Next review date : Thursday, November 24,2016
Disclaimer: This site is intended to be flexible and frequently updated. While every effort has been made to ensure accuracy, all information should be verified.