Gastroenterology  |  Colorectal Cancer Pathway - Risk Factors


Colorectal Cancer Pathway - Risk Factors

1. Age >50:

  • The risk of CRC increases with age. Over 90% of cases are in individuals over the age of 50 years.

2. Past history adenoma/ CRC/IBD:

  • An increased risk of CRC is identified in individuals with a personal history of CRC, colorectal adenomas or inflammatory bowel disease.
  • Studies suggest that individuals with longstanding (>10yrs), extensive Ulcerative Colitis or Crohns Disease have a CRC risk of 2% by 10yrs, 8% by 20yrs and 18% by 30years.

3. Family History CRC:

  • Individuals with a family history of CRC may have an increased risk of developing disease. A full family history is needed and should include any CRC or adenomas in 1st or 2nd degree relatives and the age of diagnosis. 
  • 1st degree relatives- parents, siblings, children.
  • 2nd degree relative- grandparents, aunts, uncles, nieces, nephews. For more information on risk see the CRC Surveillance recommendations

Last updated : Wednesday, November 25, 2015
Next review date : Thursday, November 24,2016

Disclaimer: This site is intended to be flexible and frequently updated. While every effort has been made to ensure accuracy, all information should be verified.