Sexual Health  |  Chlamydia Pathway - Treatment of uncomplicated chlamydia




Sexual Health

Chlamydia Pathway - Treatment of uncomplicated chlamydia

Uncomplicated chlamydia:

  • in men and women, either of the following are recommended as first-line:
    • azithromycin 1g orally as a single dose
    • doxycycline 100mg orally twice daily for 7 days
      NB: Doxycycline is more effective for rectal infection and for symptomatic patients. Consider using for patients on SSRI's or other QT prolonging drugs including non-prescribed opioids
  • in pregnancy or breast-feeding:
    • azithromycin 1g orally as a single dose (pregnancy category B1):
      • recommended first-line for treatment by the World Health Organization (WHO)
    • erythromycin 500mg orally twice daily for 14 days
    • erythromycin 500mg orally four times daily for 7 days
    • amoxicillin 500mg orally three times daily for 7 days


Rectal infection in men:

  • consider discussing patients with rectal infection with sexual health clinician
  • consider lymphogranuloma venereum (LVG):
    • if diagnosed, or suspected on clinical grounds, doxycycline is recommended
  • if the patient has had a positive nucleic acid amplification test (NAAT/PCR) and the patient reports rectal symptoms, or is a contact of someone with LGV, refer to sexual health clinic for further assessment including LGV testing.


Last updated : Monday, April 09, 2018
Next review date : Tuesday, April 09,2019


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