Health of Older People  |  Uncomplicated Dementia Pathway - Differential Diagnosis




Health of Older People

Uncomplicated Dementia Pathway - Differential Diagnosis

Normal age-related memory decline is characterised by:

  • Subjective memory concern.
  • Mild episodic memory impairment.
  • Preserved procedural and semantic memory.
  • Possible mild non-memory cognitive dysfunction (e.g. attention).
  • No functional impairment or behavioural abnormalities.


Medical conditions associated with memory loss include:

  • Mental illness e.g. depression
  • Cerebrovascular disease
  • Neurodegenerative disease e.g. Alzheimer's disease, Parkinson's disease, Creutzfeldt-Jakob disease
  • Medications (e.g. anti-cholinergics, beta blockers, opiates)
  • Substance misuse/dependence (e.g. alcohol, benzodiazepines, opiates)
  • Brain tumour and infections
  • Head injury
  • Epilepsy
  • Chronic pain, anxiety, stress
  • Sleep disorders
  • Thyroid disease
  • Malnutrition, vitamin deficiencies
  • Delirium

[BPAC 2008]



Last updated : Friday, August 21, 2015
Next review date : Saturday, August 20,2016


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